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| IJCEM Copyright © 2008-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711 |
Int J Clin Exp Med 2012;5(1):80-86
Original Article
Preoperative localization of parathyroid lesion: diagnostic usefulness of color
doppler ultrasonography
Afshin mohammadi, Farzad Moloudi, Mohammad Ghasemi-rad
Department of Radiology, Urmia University of Medical Sciences, Urmia, West Azerbaijan, Iran; Student research committee, Urmia
University of medical Sciences. Urmia, Iran; Genius and talented student organization, student research committee, Urmia University of
medical Sciences. Urmia, Iran
Received November 21, 2011; accepted December 27, 2011; Epub January 15, 2012; Published January 31, 2012
Abstract: Introduction: Recently, minimally invasive parathyroidectomy (MIP) has been developed and is gaining popularity among
surgeons. For this reason, preoperative localization is playing an important role to detect the precise location of the affected gland and
to increase the success rate. Material and methods: From June 2007 to June 2011, 56 consecutive patients (11 men and 45 women)
with primary or secondary hyperparathyroidism in our center underwent Gray scale, color Doppler and 99m-Tc MIBI scan prior to
operative management of parathyroid lesions. Results: The sensitivity, specificity and accuracy of US and MIBI scan for pHPT was 88%,
94%, 91% and 70%, 100% and 85% respectively. In patients with sHPT, the sensitivity, specificity and accuracy of US and MIBI scan
was 54%, 93%, 76% and 25%, 100% and 72.9% respectively. The overall sensitivity of combined US and MIBI scan in pHPT and sHPT
was 97% and 45% respectively. The overall sensitivity, specificity and accuracy of CDUS in diagnosis of parathyroid lesions in pHPT
and sHPT is 97%, 100%, 98.6% and 62%, 100% and 83% respectively. Conclusion: The overall sensitivity and specificity of US and
MIBI in preoperative localization of parathyroid adenoma in sHPT is lower than pHPT and performing CDUS can increases the overall
sensitivity and specificity of imaging methods in accurate localization of parathyroid lesion. (IJCEM1111004).
Keywords: Preoperative localization, parathyroid lesion, diagnosis, color doppler, ultrasonography
Address all correspondence to:
Dr. Afshin Mohammadi
Department of Radiology
Urmia University of Medical Sciences
Urmia, West-Azerbaijan, Iran.
Tel: 984413455810; Fax: +98441_2353561
E-mail: Mohamadi_afshin@yahoo.com
Original Article
Preoperative localization of parathyroid lesion: diagnostic usefulness of color
doppler ultrasonography
Afshin mohammadi, Farzad Moloudi, Mohammad Ghasemi-rad
Department of Radiology, Urmia University of Medical Sciences, Urmia, West Azerbaijan, Iran; Student research committee, Urmia
University of medical Sciences. Urmia, Iran; Genius and talented student organization, student research committee, Urmia University of
medical Sciences. Urmia, Iran
Received November 21, 2011; accepted December 27, 2011; Epub January 15, 2012; Published January 31, 2012
Abstract: Introduction: Recently, minimally invasive parathyroidectomy (MIP) has been developed and is gaining popularity among
surgeons. For this reason, preoperative localization is playing an important role to detect the precise location of the affected gland and
to increase the success rate. Material and methods: From June 2007 to June 2011, 56 consecutive patients (11 men and 45 women)
with primary or secondary hyperparathyroidism in our center underwent Gray scale, color Doppler and 99m-Tc MIBI scan prior to
operative management of parathyroid lesions. Results: The sensitivity, specificity and accuracy of US and MIBI scan for pHPT was 88%,
94%, 91% and 70%, 100% and 85% respectively. In patients with sHPT, the sensitivity, specificity and accuracy of US and MIBI scan
was 54%, 93%, 76% and 25%, 100% and 72.9% respectively. The overall sensitivity of combined US and MIBI scan in pHPT and sHPT
was 97% and 45% respectively. The overall sensitivity, specificity and accuracy of CDUS in diagnosis of parathyroid lesions in pHPT
and sHPT is 97%, 100%, 98.6% and 62%, 100% and 83% respectively. Conclusion: The overall sensitivity and specificity of US and
MIBI in preoperative localization of parathyroid adenoma in sHPT is lower than pHPT and performing CDUS can increases the overall
sensitivity and specificity of imaging methods in accurate localization of parathyroid lesion. (IJCEM1111004).
Keywords: Preoperative localization, parathyroid lesion, diagnosis, color doppler, ultrasonography
Address all correspondence to:
Dr. Afshin Mohammadi
Department of Radiology
Urmia University of Medical Sciences
Urmia, West-Azerbaijan, Iran.
Tel: 984413455810; Fax: +98441_2353561
E-mail: Mohamadi_afshin@yahoo.com
