International Journal of Clinical and Experimental Medicine

Editor-in-Chief:
Ping Wang, MD
The Feinstein Institute for Medical Research
Albert Einstein College of Medicine
E-mail: pwang@nshs.edu

Editor-in-Chief Assistant
Asha Jacob Varghese, PhD
The Feinstein Institute for Medical Research
E-mail: avarghes@nshs.edu

Assistant Editor
Madeline Ann Quinn
The Feinstein Institute for Medical Research
E-mail: maquinn@nshs.edu

Associate Editor-in-Chief
Alfred Ayala, PhD
Brown University School of Medicine
E-mail: AAyala@lifespan.org

Associate Editor-in-Chief:
Dengshun Wang, MD, PhD
University of Wisconsin-Madison, WI
E-mail: dwang6@wisc.edu

International Journal of Clinical and Experimental Medicine
---IJCEM: ISSN 1940-5901

Published by: e-Century Publishing Corporation

Editorial Board (In alphabetical order) Editorial Board Policies

Edward Abraham, MD, University of Alabama School of Medicine

Jonathan Steven Alexander, PhD, LSU Health Sciences Center

Burton M. Altura, PhD, SUNY Downstate Medical Center

Craig S. Atwood, PhD, University of Wisconsin-Madison

Alfred Ayala, PhD, Brown University School of Medicine

Linnea M Baudhuin, PhD, Mayo Clinic Rochester

Alexander Boldyrev, PhD, Moscow State University, Russia

Robert Bowser, PhD, University of Pittsburgh

David D. Brand, PhD, Universisty of Tennessee at Memphis

Christine Van Broeckhoven, PhD , DSc, VIB, University of Antwerp, Belgium

Luigi Buonaguro, MD, National Cancer Institute "Giovanni Pascale", Italy

Jeffrey M Burns, MD, University of Kansas

Laura Calzà, PhD, University of Bologna, Italy

Justo P Castaño, PhD, Universidad de Cordoba, Spain

Rudolph J Castellani, MD, University of Maryland

Sulie L Chang, PhD, Seton Hall University, NJ

Raymond Chuen-Chung Chang, PhD, University of Hong Kong

Susan Chubinskaya, PhD, Rush Medical University

Pawel S Ciborowski, PhD, University of Nebraska

Mark G Clemens, PhD, University of North Carolina

Richard Coico, PhD, Temple University

Cristoforo Comi, MD, PhD, Maggiore Hospital, Italy

James A Cook, PhD, Medical University of South Carolina

Fabio Coppedè, PhD, University of Pisa, Italy

Roland S Croner, MD, University Hospital Erlangen, Germany

A. Claudio Cuello, MD, DSc, McGill University, Canada

Edwin A Deitch, MD, New Jersey Medical School of UMDNJ

Mario Diaz, PhD, University of La Laguna, Spain

Charles A Dinarello, MD,University of Colorado

Jon Dobson, PhD, University of Florida

Richard C Dodel, PhD, Philipps-University Marburg, Germany

Sylvain Doré, PhD, Johns Hopkins University

Ulrich Eisel, PhD, UNiversity of Groningen, Netherlands

Matthew Farrer, PhD, Mayo Clinic Jacksonville

Vincenza Frisardi, MD, University of Bari, Italy

Daniela Galimberti, PhD, University of Milan, Italy

Armen Y Gasparyan, MD, PhD, Dudley Group of Hospitals, UK

Roberta Ghidoni, PhD, IRCCS S. Giovanni di Dio, Brescia Italy

Othman Ghribi, PhD, University of North Dakota

Anna R Giovagnoli, MD, Fondazione IRCCS Istituto Neurologico C Besta

Brian Giunta, MD, University of South Florida

Zihua Gong, MD, PhD, University of Texas MD Anderson Cancer Center

Sanna M Goyert, PhD, City College of New York Medical School

Daniel A Grande, PhD, Feinstein Institute for Medical Research

Jesús Avila de Grado, PhD, CBMSO, Spain

Zhizhong Guan, PhD, MD, Guiyang Medical College, China

Katrina A Gwinn, MD, NIH/NINDS, Bethesda,

David B Hoyt, MD, FACS,University of California, Irvine

Ke-Qin Hu, MD,, University of California at Irvine

Xudong Huang, PhD, Harvard Medical School

Mook-Jung Inhee, PhD, Seoul National University, Korea

Khalid Iqbal, PhD, Institute for Basic Research of New York State

Hieronim Jakubowski, PhD, UMDNJ-New Jersey Medical School

Kurt A Jellinger, MD, University of Vienna, Austria

Hong-Fang Ji, PhD, Shandong University of Technology, China

Gregory A Jicha, MD, PhD, University of Kentucky

Jeffrey A Johnson, PhD, University of Wisconsin-Madison

Emad Kandil, MD, Tulane University, New Orleans, LA

Kikuya Kato, MD, PhD, OMCCCD, Japan

Patrick Kehoe, PhD, University of Bristol, UK

Haseeb A Khan, PhD, King Saud University, Saudi Arabia

Christoph Kleinschnitz, MD, University of Wuerzburg, Germany

Neil W Kowall, MD, Boston University

Aseem Kumar, PhD, Laurentian University, Canada

Toshihiro Kushibiki, PhD, Osaka University, Japan

Antonio La Cava, MD, PhD, University of California Los Angeles

Bernard Le Foll, MD, PhD, University of Toronto, Canada

Charles H Lang, PhD, The Pennsylvania State University

Raquel F Leal, MD, PhD, University of Campinas, Brazil

Myeong Soo Lee , PhD, Universities of Exeter & Plymouth, UK

Piotr Lewczuk, PhD, Universitätsklinikum Erlangen, Germany

Chunying Li, MD, PhD, Fourth Military Medical University, China

Fengzhi Li, PhD, Roswell Park Cancer Institute

Gang Li, MD, PhD, University of British Columbia, Canada

Guojun Li, MD, PhD, M.D. Anderson Cancer Center

Jian-Dong Li, PhD, University of Rochester

Jianhua Li, PhD, Penn State University

Jianyong Li, PhD, Virginia Polytechnic Institute and State University

Kui Li, MD, PhD, The University of Tennessee at Memphis

Li Li, PhD, Wayne State University

Lian Li, PhD, Emory University

Liwu Li, PhD, Virginia Polytechnic Institute and State University

P. Andy Li, MD, PhD, North Carolina Central University

Shuxin Li, MD, PhD, UT Southwestern Medical Center at Dallas

Qianjun Li, PhD, University of Alabama at Birmingham

Qingbo K. Li, PhD, University of Illinois at Chicago

Wenjun Li, PhD, University of Massachusetts at Worcester

Willis Li, PhD, University of California at San Diego

Xian C. Li, PhD, Harvard Medical School

Xiang-An Li, PhD, University of Kentucky, Lexington, KY

Xuhang Li, PhD, Johns Hopkins University

Zhi-Ren Liu, PhD, Georgia State University

Yuying Liang, PhD, Emory University

Antonio Liras, PhD, Universidad Complutense de Madrid, Spain

Dongmin Liu, PhD, Virginia Tech

Ming Liu, PhD, The University of Toledo

Philip K Liu, PhD, Harvard University

Rui-Ming Liu, PhD, University of Alabama at Birmingham

Tao Liu, PhD, University of New South Wales, Australia

Wanguo Liu, PhD, Louisiana State University

Yusen Liu, PhD, The Ohio State University

Zhenguo Liu, MD, PhD, Ohio State University

Zhenqiu Liu, PhD, University of Maryland

B Jack Longley, MD, University of Wisconsin at Madison

Jes u s M L o pez Arrieta, PhD, Universitario La Paz-Cantoblanco, Spain

Kun Ping Lu, MD, PhD, Harvard Medical School

Hinh Ly, PhD, Emory University

Corrado P. Marini, MD, FACS, Albert Einstein College of Medicine

Patrizia Mecocci, PhD, University of Perugia, Italy

Xianzhong Meng, MD, University of Colorado at Denver

Joseph L Messina, PhD, University of Alabama at Birmingham

Andrei C Miu, PhD, Babes-Bolyai University, Romania

Patricia Molina, MD, PhD, Louisiana State University HSC

Roberto Monastero, MD, PhD, University of Palermo, Italy

Paula Isabel da Silva Moreira, PhD, University of Coimbra, Portugal

Laura Morelli PhD, Leloir Institute Foundation, Argentina

Gerald Muench, PhD, University of Western Sydney, Australia

Takahiko Nakagawa, MD, PhD, University of Colorado Denver

Steve Nelson, M.D., FCCP, LSU School of Medicine at New Orleans

Yasumasa Ohyagi, MD, PhD, Kyushu University, Japan

Toru Ouchi, PhD, University of Chicago

Z. Kevin Pan, MD, PhD, University of Toledo

Francesco Panza, MD, PhD, University of Bari, Italy

Narayanan Parameswaran, PhD, Michigan State University

John K. Park, MD, PhD, National Institutes of Health

Jin-Jing Pei, MD, PhD, Karolinska Institutet, Sweden

Silvia Pellegrini, PhD, University of Pisa, Italy

Milena Penkowa, MD, PhD, University of Copenhagen, Denmark

Cláudia Maria Fragão Pereira, PhD, University of Coimbra, Portugal

George Perry, PhD, University of Texas at San Antonio

Philip A. Philip, MD, PhD, Wayne State University School of Medicine

M . C ristina Polidori, MD, PhD, Ruhr-University of Bochum, Germany

Luigi Puglielli, PhD, University of Wisconsin at Madison

Cheng-Kui Qu, MD, PhD, Case Western Reserve University

Rajiv Ratan, MD, PhD, Burke Rehabilitation Hospital

T. S. Ravikumar, MD, FACS, Geisinger Health System

Marcella Reale, PhD, The G. d'Annunzio University, Italy

V. Prakash Reddy, PhD, Missouri University of Science & Technology

Jill C. Richardson, PhD, Imperial College London, UK

Beatriz García Rodríguez, MD, UNED, Madrid, Spain

Andrej A. Romanovsky, MD, PhD, St. Joseph’s Hospital

Laurel W. Rice, MD, University of Wisconsin-Madison

Joaquin Del Rio, MD, University of Navarra, Spain

Andrew I. Schafer, MD, Cornell University

Fabio A. B. Schutz, MD, Harvard Medical School

Martin G. Schwacha, PhD, University of Texas at San Antonio

Jalid Sehouli, MD, PhD, University Medicine of Berlin, Germany

Alessandro Serretti, MD, PhD, University of Bologna, Italy

Jin-Xiong She, PhD, Medical College of Georgia

Thomas B. Shea, PhD, University of Massachusetts Lowell

H. Hank Simms, MD, Albert Einstein Medical Center

Folke Sjöberg, MD, University hospital, Linköping, Sweden

Gianfranco Spalletta, MD, PhD, IRCCS Santa Lucia Foundation, Italy

Michael G. Stewart, PhD, Open University, UK

Wolfgang J. Streit, PhD, University of Florida College of Medicine

Russell Swerdlow, MD, University of Kansas

Csaba Szabó, MD, PhD, University of Texas Galveston

Xiao-Di Tan, MD, Northwestern University-Chicago

Sima T. Tarzami, PhD, Mount Sinai School of Medicine

Tanja Maria Michel, MD, RWTH Aachen University, Germany

J.C. de la Torre, MD, PhD, Banner Sun Health Research Institute

Kevin J. Tracey, MD, Feinstein Institute for Medical Research

Janusz Tucholski, PhD, University of Alabama at Birmingham

David J. Tweardy, MD, Baylor College of Medicine

Chiayeng Wang, PhD, University of Illinois at Chicago

Cun-Yu Wang , PhD, DDS, University of California at Los Angeles

Donna Wang, MD, Michigan State University

Haichao Wang, PhD, New York University School of Medicine

Hong Wang, PhD, Monell Chemical Senses Center

Hongbing Wang, PhD, University of Maryland

Hong-Sheng Wang, PhD, University of Cincinnati

Jian Wang, MD, PhD, Johns Hopkins University

Jian-Ying Wang, MD, PhD, University of Maryland

Jinxi Wang, MD, PhD, University of Kansas

Li-E Wang, MD, M.D. Anderson Cancer Center

Meijing Wang, MD, Indiana University School of Medicine

Q. Jane Wang, PhD, University of Pittsburgh, PA

Ruobing Wang, MD, PhD, Seattle Biomedical Research Institute

Tianyi Wang, PhD, University of Pittsburgh

Xin Wang, PhD, Harvard Medical School

Ya Wang, MD, PhD, Emory University

Yanggan Wang, MD, PhD, Emory University

Yong-Xiao Wang, MD, PhD, Albany Medical College

Yuan-Min Wang, MD, PhD, University of Sydney, Australia

Zhao-Wen Wang, MD, PhD, University of Connecticut

Ze Wang, PhD, University of Pennsylvania

H. Christian Weber, MD, Boston University

Qingyi Wei, MD, PhD, M. D. Anderson Cancer Center

David L. Williams, PhD, East Tennessee State University

Jun Wu, MD, PhD, Third Military Medical University, China

Jun Xie, PhD, University of Oklahoma

Zhigang Xiong MD , PhD, Robert S. Dow Neurobiology Laboratories

Huaxi Xu, PhD, Burnham Institute for Medical Research

Liang Xu, MD, PhD, University of Kansas

Shi Du Yan, MD, Columbia University in the City of New York

Qinglin Yang, MD, PhD, University of Alabama at Birmingham

Shu-Hui C. Yen, PhD, Mayo Clinic College of Medicine

Chunshui Yu, MD, Tianjin Medical University, China

Sarah Y. Yuan, MD, PhD, University of California at Davis

Inga Zerr, MD, Georg August University Göttingen, Germany

Henrik Zetterberg, MD, PhD, University of Gothenburg, Sweden

Chunxiang Zhang, MD,PhD, New Jersey Medical School

Jianliang Zhang, PhD, University of Florida

Jian-Ting Zhang , PhD, Indiana University

Kezhong Zhang, PhD, Wayne State University

Ming Zhang, PhD, Northwestern University

Miqin Zhang, PhD, University of Washington-Seattle

Ping Zhang, MD, PhD, Louisiana State University HSC

Qi Zhang, PhD, Old Dominion University

Wenhong Zhang, MD, PhD, Fudan University, China

Xiaoliang Zhang, PhD, University of California at San Francisco

Xuming Zhang, DVM, PhD, University of Arkansas

Yan Zhang, PhD, Beijing University, China

Zhengdong Zhang , MD, PhD, Nanjing Medical University, China

Zhixin (Jason) Zhang, PhD, University of Nebraska

Zili Zhang, MD, PhD, Oregon Health & Science University

Jing Zheng, PhD, University of WIsconsin-Madison

Pan Zheng, MD, PhD, University of Michigan at Ann Arbor

Song-Guo Zheng, MD, University of Southern California

Jiang-Ning Zhou, MD, PhD, Univ. of Science & Technology of China

Basilia Zingarelli, MD, PhD, University of Cincinnati

Founding Editorial Board

Edward Abraham, MD, Professor and Chair, University of Alabama School of Medicine, Birmingham, AL, USA
Alfred Ayala, PhD, Professor, Department of Surgery, Brown University School of Medicine, Providence, RI, USA
Edwin A. Deitch, MD, Professor and Chair, Department of Surgery, The New Jersey Medical School of UMDNJ, Newark, NJ, USA
Charles A. Dinarello, MD, Professor, Member of National Academy of Sciences, University of Colorado School of Medicine, Denver, CO, USA
David B. Hoyt, MD, FACS, Professor and Chair, Department of Surgery, University of California, Irvine, USA
Khalid Iqbal, PhD, Professor and Chair, NYS Institute for Basic Research, The City University of New York, Staten Island, New York
B Jack Longley, MD, Professor and Vice Chair, Department of Dermatology, University of Wisconsin School of Medicine, Madison, WI, USA
Steve Nelson, MD, CM, FCCP, Professor and Dean, LSUHSC’s School of Medicine, New Orleans, LA, USA
Edith A. Perez, MD, Professor and Director, Mayo Clinic Cancer Center, Jacksonville, FL, USA
T. S. Ravikumar, MD, FACS , Professor and Chairman, Department of Surgery, North Shore University Hospital, Manhasset, NY, USA
Daniel Remick, MD, Professor and Chair, Department of Pathology, Boston University School of Medicine, Boston, MA, USA
Laurel W. Rice, MD, Professor and Chair, Department of Obstetrics & Gynecology, University of Wisconsin School of Medicine, Madison, WI, USA
Andrew I. Schafer, MD, Professor and Chair, Department of Medicine, Weill Cornell Medical College, Cornell University, New York, NY, USA
Kevin J. Tracey, MD, Professor, Director and CEO, The Feinstein Institute for Medical Research, Manhasset, NY, USA
Cun-Yu Wang , PhD, DDS, Professor and Chair, UCLA School of Dentistry, University of California, Los Angeles , USA
Jian-Ying Wang, MD, PhD, Professor and Associate Chair, Department of Surgery, University of Maryland School of Medicine, Baltimore MD, USA