 | |  | |  | |  | |  | |  | |  | |  |
| IJCEM Copyright © 2008-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711 |
Int J Clin Exp Med 2013;6(10):1010-1014
Case Report
Unilateral hydronephrosis caused by invasive mole: a case report
Hai-Yan Zhang, Wei Wu, Jin Zhu
Department of Gynecology, The Obstetrics and Gynecology Hospital, Shanghai Medical College, Fudan University, No.419 Fangxie
Road, Shanghai, China
Received October 12, 2013; Accepted October 22, 2013; Epub October 25, 2013; Published October 30, 2013
Abstract: Invasive mole belongs to gestational trophoblastic neoplasm, which is a highly curable group of pregnancy-related tumors.
However, approximately 20% of gestational trophoblastic tumors will be resistant to or relapsed after initial chemotherapy. These
resistant and relapsed lesions will require salvage chemotherapy with or without surgery. It is still unclear which regimens are the
most effective and least toxic. Here, we report a case of unilateral hydronephrosis presenting 1 week after a history of curettage
because of a hydatidiform mole. With the combination treatments of chemotherapy and surgery, the patient was cured.
(IJCEM1310018).
Keywords: Gestational trophoblastic neoplasm, hydronephrosis, chemotherapy, surgery
Address correspondence to: Dr. Jin Zhu, Department of Gynecology, The Obstetrics and Gynecology Hospital, Shanghai Medical
College, Fudan Univer-sity, No.419 Fangxie Road, Shanghai, China. Tel: +86-21-33189900; Fax: +86-21-63455090; E-mail:
zhujin_88@126.com
Case Report
Unilateral hydronephrosis caused by invasive mole: a case report
Hai-Yan Zhang, Wei Wu, Jin Zhu
Department of Gynecology, The Obstetrics and Gynecology Hospital, Shanghai Medical College, Fudan University, No.419 Fangxie
Road, Shanghai, China
Received October 12, 2013; Accepted October 22, 2013; Epub October 25, 2013; Published October 30, 2013
Abstract: Invasive mole belongs to gestational trophoblastic neoplasm, which is a highly curable group of pregnancy-related tumors.
However, approximately 20% of gestational trophoblastic tumors will be resistant to or relapsed after initial chemotherapy. These
resistant and relapsed lesions will require salvage chemotherapy with or without surgery. It is still unclear which regimens are the
most effective and least toxic. Here, we report a case of unilateral hydronephrosis presenting 1 week after a history of curettage
because of a hydatidiform mole. With the combination treatments of chemotherapy and surgery, the patient was cured.
(IJCEM1310018).
Keywords: Gestational trophoblastic neoplasm, hydronephrosis, chemotherapy, surgery
Address correspondence to: Dr. Jin Zhu, Department of Gynecology, The Obstetrics and Gynecology Hospital, Shanghai Medical
College, Fudan Univer-sity, No.419 Fangxie Road, Shanghai, China. Tel: +86-21-33189900; Fax: +86-21-63455090; E-mail:
zhujin_88@126.com
