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| IJCEM Copyright © 2008-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711 |
Int J Clin Exp Med 2013;6(10):851-860
Review Article
A practical guide to treatment of infantile hemangiomas of the head and neck
Jia Wei Zheng, Ling Zhang, Qin Zhou, Hua Ming Mai, Yan An Wang, Xin Dong Fan, Zhong Ping Qin, Xv Kai Wang, Yi Fang Zhao
Department of Oral and Maxillofacial Surgery, Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School
of Medicine, No. 639, Zhi Zao Ju Road, Shanghai 200011, China; Department of Oral and Maxillofacial Surgery, School of Stomatology,
Guangxi Medical University, No. 10, Shuang Yong Road, Nanning 530021, Guangxi Province, China; Department of Radiology, Ninth
People’s Hospital, Shanghai Jiao Tong University School of Medicine, No. 639, Zhi Zao Ju Road, Shanghai 200011, China; Special
Department of Hemangioma, Tumor Hospital of Linyi City, No. 6, Lingyuan East Street, Linyi 276001, Shandong Province, China;
Department of Oral and Maxillofacial Surgery, School of Stomatology, China Medical University, No. 143, North Nanjing Road, Heping
District, Shenyang 110002, Liaoning Province, China; Department of Oral and Maxillofacial Surgery, School of Stomatology, Wuhan
University, No. 237, Luo Yu Road, Wuhan 430079, Hubei Province, China
Received September 11, 2013; Accepted October 22, 2013; Epub October 25, 2013; Published October 30, 2013
Abstract: Infantile hemangiomas are the most common benign vascular tumors in infancy and childhood. As hemangioma could
regress spontaneously, it generally does not require treatment unless proliferation interferes with normal function or gives rise to risk of
serious disfigurement and complications unlikely to resolve without treatment. Various methods for treating infant hemangiomas have
been documented, including wait and see policy, laser therapy, drug therapy, sclerotherapy, radiotherapy, surgery and so on, but none
of these therapies can be used for all hemangiomas. To obtain the best treatment outcomes, the treatment protocol should be
individualized and comprehensive as well as sequential. Based on published literature and clinical experiences, we established a
treatment guideline in order to provide criteria for the management of head and neck hemangiomas. This protocol will be renewed and
updated to include and reflect any cutting-edge medical knowledge, and provide the newest treatment modalities which will benefit our
patients. (IJCEM1309005).
Keywords: Hemangiomas, treatment, head and neck, sclerotherapy, drug therapy
Address correspondence to: Dr. Jia Wei Zheng, Department of Oral and Maxillofacial Surgery, Ninth People’s Hospital, College of
Stomatology, Shanghai Jiao Tong University School of Medicine, No. 639, Zhi Zao Ju Road, Shanghai 200011, China. Tel: +86 21
23271063; Fax: +86 21 63121780; E-mail: davidzhengjw@sjtu.edu.cn
Review Article
A practical guide to treatment of infantile hemangiomas of the head and neck
Jia Wei Zheng, Ling Zhang, Qin Zhou, Hua Ming Mai, Yan An Wang, Xin Dong Fan, Zhong Ping Qin, Xv Kai Wang, Yi Fang Zhao
Department of Oral and Maxillofacial Surgery, Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School
of Medicine, No. 639, Zhi Zao Ju Road, Shanghai 200011, China; Department of Oral and Maxillofacial Surgery, School of Stomatology,
Guangxi Medical University, No. 10, Shuang Yong Road, Nanning 530021, Guangxi Province, China; Department of Radiology, Ninth
People’s Hospital, Shanghai Jiao Tong University School of Medicine, No. 639, Zhi Zao Ju Road, Shanghai 200011, China; Special
Department of Hemangioma, Tumor Hospital of Linyi City, No. 6, Lingyuan East Street, Linyi 276001, Shandong Province, China;
Department of Oral and Maxillofacial Surgery, School of Stomatology, China Medical University, No. 143, North Nanjing Road, Heping
District, Shenyang 110002, Liaoning Province, China; Department of Oral and Maxillofacial Surgery, School of Stomatology, Wuhan
University, No. 237, Luo Yu Road, Wuhan 430079, Hubei Province, China
Received September 11, 2013; Accepted October 22, 2013; Epub October 25, 2013; Published October 30, 2013
Abstract: Infantile hemangiomas are the most common benign vascular tumors in infancy and childhood. As hemangioma could
regress spontaneously, it generally does not require treatment unless proliferation interferes with normal function or gives rise to risk of
serious disfigurement and complications unlikely to resolve without treatment. Various methods for treating infant hemangiomas have
been documented, including wait and see policy, laser therapy, drug therapy, sclerotherapy, radiotherapy, surgery and so on, but none
of these therapies can be used for all hemangiomas. To obtain the best treatment outcomes, the treatment protocol should be
individualized and comprehensive as well as sequential. Based on published literature and clinical experiences, we established a
treatment guideline in order to provide criteria for the management of head and neck hemangiomas. This protocol will be renewed and
updated to include and reflect any cutting-edge medical knowledge, and provide the newest treatment modalities which will benefit our
patients. (IJCEM1309005).
Keywords: Hemangiomas, treatment, head and neck, sclerotherapy, drug therapy
Address correspondence to: Dr. Jia Wei Zheng, Department of Oral and Maxillofacial Surgery, Ninth People’s Hospital, College of
Stomatology, Shanghai Jiao Tong University School of Medicine, No. 639, Zhi Zao Ju Road, Shanghai 200011, China. Tel: +86 21
23271063; Fax: +86 21 63121780; E-mail: davidzhengjw@sjtu.edu.cn
