IJCEM Copyright © 2008-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711
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Int J Clin Exp Med 2013;6(10):956-959
Original Article
Effects of different inhaled oxygen concentration and end-expiratory positive
pressure on Pa-etCO2 in patients undergoing gynecological laparoscopic surgery
Guiqi Geng, Jingyi Hu, Shaoqiang Huang
Department of Anesthesiology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China
Received September 7, 2013; Accepted October 5, 2013; Epub October 25, 2013; Published October 30, 2013
Abstract: There is some disagreement about whether the PetCO2 is reliable in predicting the PaCO2 in laparoscopic procedures with
CO2 inflation. The aim of the present study is to measure the Pa-etCO2 differences over time in healthy patients undergoing
gynecological laparoscopic surgery with different ventilation methods. Methods: After intubation, patients were randomized into three
groups. The patients in group A were ventilated with air/O2 (FiO2 = 50%) and supplied with PEEP (5cmH2O). The patients in group B
were ventilated with 50% oxygen while the patients in group C were ventilated with 100% oxygen. All patients were conducted with
volume-controlled ventilation. PetCO2 and PaCO2 were measured at baseline, one minute after intubation, every 30 min thereafter and
5 minutes after deflation of pneumoperitoneum. Results: The differences in Pa-etCO2 between groups A, B and C were insignificant
one minute after intubation. The Pa-etCO2 in group B and C significantly increased compared with that in group A at other time points
after intubation. Conclusion: Oxygen concentration and positive end-expiratory pressure could affect Pa-etCO2 in laparoscopic surgery
patients. (IJCEM1309003).
Keywords: FiO2, PEEP, PaCO2, PetCO2, laparoscopic surgery
Address correspondence to: Dr. Guiqi Geng, Department of Anesthesiology, Obstetrics and Gynecology Hospital, Fudan University,
No.128, Shenyang Road, Shanghai 200090, China. Tel: +86-21-63455050-6868; Fax: +86-21-63455090; E-mail:
mzgengguiqi@163.com
