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Int J Clin Exp Med 2013;6(9):845-850
Case Report
Diagnosis and treatment of hepatic tuberculosis: report of five cases and review of
literature
Zheng Wu, Wan-Li Wang, Ying Zhu, Ji-Wen Cheng, Jian Dong, Mu-Xing Li, Liang Yu, Yi Lv, Bo Wang
Department of Hepatobiliary Surgery, First Affiliated Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an 710061, Shaanxi,
China; Department of General Surgery, Bazhong Central Hospital, Bazhong 636000, Sichuan, China; Institute of Advanced Surgical
Technology and Engineering, Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China
Received August 9, 2013; Accepted August 27, 2013; Epub September 25, 2013; Published September 30, 2013
Abstract: Hepatic tuberculosis is uncommon, lack of specific clinical manifestations and imaging features, so it can easily be
misdiagnosed in clinical. Herein, we discuss variety of its forms and summarize the diagnosis and treatment of hepatic tuberculosis in
this paper. Five cases of hepatic tuberculosis are described. The diagnosis, treatment and outcome of the patients are discussed.
Image examination associated with image-guided fine needle aspiration biopsy is the best diagnostic method. In our center, three
patients underwent needle biopsy and confirmed hepatic tuberculosis. In addition, two patients preoperative misdiagnosed as
cholangiocarcinoma were confirmed hepatic tuberculosis by postoperative pathology. Three patients underwent surgical procedures
along with anti-tubercular drug therapy, two patients received only anti-tubercular drug therapy. The renal post-transplantation patient
with hepatic tuberculosis eventually died of multiple organ failure (MODS). The other four patients were followed for 48~120 months,
yielding no recurrence of hepatic tuberculosis. In conclusion, hepatic tuberculosis usually associated with atypical clinical
manifestations. Image examination associated with image-guided fine needle aspiration biopsy is the best diagnostic method. Anti-TB
treatment is effective in most of cases. However, if there are indications for surgery or difficult to diagnose, surgical procedures along
with anti-tubercular drug therapy could be adopted. (IJCEM1308010).
Keywords: Liver mass, tuberculoma, tuberculosis, TB, anti-TB
Address correspondence to: Dr. Bo Wang, Department of Hepatobiliary Surgery, First Affiliated Hospital, School of Medicine, Xi’an
Jiaotong University, No. 277 West Yanta Road, Xi’an 710061, People’s Republic of China. E-mail: bobwang75@126.com
Case Report
Diagnosis and treatment of hepatic tuberculosis: report of five cases and review of
literature
Zheng Wu, Wan-Li Wang, Ying Zhu, Ji-Wen Cheng, Jian Dong, Mu-Xing Li, Liang Yu, Yi Lv, Bo Wang
Department of Hepatobiliary Surgery, First Affiliated Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an 710061, Shaanxi,
China; Department of General Surgery, Bazhong Central Hospital, Bazhong 636000, Sichuan, China; Institute of Advanced Surgical
Technology and Engineering, Xi’an Jiaotong University, Xi’an 710061, Shaanxi, China
Received August 9, 2013; Accepted August 27, 2013; Epub September 25, 2013; Published September 30, 2013
Abstract: Hepatic tuberculosis is uncommon, lack of specific clinical manifestations and imaging features, so it can easily be
misdiagnosed in clinical. Herein, we discuss variety of its forms and summarize the diagnosis and treatment of hepatic tuberculosis in
this paper. Five cases of hepatic tuberculosis are described. The diagnosis, treatment and outcome of the patients are discussed.
Image examination associated with image-guided fine needle aspiration biopsy is the best diagnostic method. In our center, three
patients underwent needle biopsy and confirmed hepatic tuberculosis. In addition, two patients preoperative misdiagnosed as
cholangiocarcinoma were confirmed hepatic tuberculosis by postoperative pathology. Three patients underwent surgical procedures
along with anti-tubercular drug therapy, two patients received only anti-tubercular drug therapy. The renal post-transplantation patient
with hepatic tuberculosis eventually died of multiple organ failure (MODS). The other four patients were followed for 48~120 months,
yielding no recurrence of hepatic tuberculosis. In conclusion, hepatic tuberculosis usually associated with atypical clinical
manifestations. Image examination associated with image-guided fine needle aspiration biopsy is the best diagnostic method. Anti-TB
treatment is effective in most of cases. However, if there are indications for surgery or difficult to diagnose, surgical procedures along
with anti-tubercular drug therapy could be adopted. (IJCEM1308010).
Keywords: Liver mass, tuberculoma, tuberculosis, TB, anti-TB
Address correspondence to: Dr. Bo Wang, Department of Hepatobiliary Surgery, First Affiliated Hospital, School of Medicine, Xi’an
Jiaotong University, No. 277 West Yanta Road, Xi’an 710061, People’s Republic of China. E-mail: bobwang75@126.com
