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Int J Clin Exp Med 2013;6(8):720-723
Original Article
Bilateral sudden hearing loss following habitual abortion: a case report and review
of literature
Tuanfang Yin, Fengying Huang, Jihao Ren, Wei Liu, Xing Chen, Lihua Li, Dinghua Xie, Yongde Lu
Department of Otolaryngology-Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan,
China, 410011; Department of Obstetrics and Gynecology, The Second Xiangya Hospital, Central South University, Changsha, Hunan,
China, 410011
Received July 30, 2013; Accepted August 18, 2013; Epub September 1, 2013; Published September 15, 2013
Abstract: Sudden sensorineural hearing loss (SSNHL) is usually unilateral and can be associated with tinnitus and vertigo. The most
common causes of this disease are known to be the vascular and viral agents, but immune disorders are involved in the development
of sudden deafness. The antiphospholipid syndrome (APS) is an acquired autoimmune system disorder, which is defined as the
presence of antiphospholipid antibodies (APA) in the patient’s blood, then cause venous and/or arterial thrombosis in various organs
of the body, for example, thrombosis can occur in the placenta and/or the inner ear. As a result, it can cause abortion and/or sudden
deafness. Bilateral SSNHL following habitual abortion is a rare clinical event. Here, we report a case of 32-year-old woman who
presented with bilateral sudden hearing loss following recurrent pregnancy loss (RPL) as the first manifestation of primary
antiphospholipid syndrome. Combine the literature, the diagnosis, clinical implication and treatment are discussed. (IJCEM1307022).
Keywords: Sudden sensorineural hearing loss (SSNHL), autoimmune disease, habitual abortion, recurrent pregnancy loss (RPL),
antiphospholipid syndrome (APS), antiphospholipid antibody (APA), anticardiolipin antibody (ACA), thrombosis
Address correspondence to: Dr. Fengying Huang, Department of Obstetrics and Gynecology, The Second Xiangya Hospital, Central
South University, Renmin Middle Road 139, Changsha, Hunan, China, 410011. Tel: +86-13874870394; E-mail: hfy6697@163.com
Original Article
Bilateral sudden hearing loss following habitual abortion: a case report and review
of literature
Tuanfang Yin, Fengying Huang, Jihao Ren, Wei Liu, Xing Chen, Lihua Li, Dinghua Xie, Yongde Lu
Department of Otolaryngology-Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan,
China, 410011; Department of Obstetrics and Gynecology, The Second Xiangya Hospital, Central South University, Changsha, Hunan,
China, 410011
Received July 30, 2013; Accepted August 18, 2013; Epub September 1, 2013; Published September 15, 2013
Abstract: Sudden sensorineural hearing loss (SSNHL) is usually unilateral and can be associated with tinnitus and vertigo. The most
common causes of this disease are known to be the vascular and viral agents, but immune disorders are involved in the development
of sudden deafness. The antiphospholipid syndrome (APS) is an acquired autoimmune system disorder, which is defined as the
presence of antiphospholipid antibodies (APA) in the patient’s blood, then cause venous and/or arterial thrombosis in various organs
of the body, for example, thrombosis can occur in the placenta and/or the inner ear. As a result, it can cause abortion and/or sudden
deafness. Bilateral SSNHL following habitual abortion is a rare clinical event. Here, we report a case of 32-year-old woman who
presented with bilateral sudden hearing loss following recurrent pregnancy loss (RPL) as the first manifestation of primary
antiphospholipid syndrome. Combine the literature, the diagnosis, clinical implication and treatment are discussed. (IJCEM1307022).
Keywords: Sudden sensorineural hearing loss (SSNHL), autoimmune disease, habitual abortion, recurrent pregnancy loss (RPL),
antiphospholipid syndrome (APS), antiphospholipid antibody (APA), anticardiolipin antibody (ACA), thrombosis
Address correspondence to: Dr. Fengying Huang, Department of Obstetrics and Gynecology, The Second Xiangya Hospital, Central
South University, Renmin Middle Road 139, Changsha, Hunan, China, 410011. Tel: +86-13874870394; E-mail: hfy6697@163.com
