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| IJCEM Copyright © 2008-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711 |
Int J Clin Exp Med 2013;6(5):372-376
Original Article
Three-step approach versus see-and-treat approach in patients with cytological
abnormalities
Nilgun Guducu, Guliz Sidar, Nuray Bassullu, Ilknur Turkmen, Ilkkan Dunder
Department of Obstetrics and Gynecology, Department of Pathology, Istanbul Bilim University, Istanbul, Turkey
Received April 17, 2013; Accepted May 11, 2013; Epub May 22, 2013; Published June 1, 2013
Abstract: The aim of this study was to compare the results of see-and-treat procedure with the classical three-step procedure in terms
of initial cytology and LEEP reports. We searched the pathology charts of patients that had LEEP were searched retrospectively and
then they were divided into 2 groups according to the presence or absence of a cervical biopsy before LEEP. There were 116 patients in
the study. Of the patients with ASCUS/LSIL cytology and a positive cervical biopsy 48.4% had CIN 2-3 at LEEP, in contrast only 19% of
the patients without a prior cervical biopsy had CIN 2-3 at LEEP (p=0.031); there was no statistically significant difference between the 2
procedures in patients with a HSIL and ASC-H smear result (p=0.726 and p=1.0 respectively). In conclusion patients with ASC-H and
HSIL cytology see-and-treat approach seems more advantageous, avoids delay in treatment, noncompliance and risk of skipping
lesions at biopsy. (IJCEM1304013).
Keywords: See-and-treat, colposcopy, CIN, overtreatment
Address correspondence to: Dr. Nilgun Guducu, Istanbul Bilim University, Department of Obstetrics and Gynecology, Kisikli cad. No:
106 Altunizade, 34696, İstanbul, Turkey. Tel: +90 0533 6404010; Fax: +90 02163250104; E-mail: nilgun.kutay@gmail.com
Original Article
Three-step approach versus see-and-treat approach in patients with cytological
abnormalities
Nilgun Guducu, Guliz Sidar, Nuray Bassullu, Ilknur Turkmen, Ilkkan Dunder
Department of Obstetrics and Gynecology, Department of Pathology, Istanbul Bilim University, Istanbul, Turkey
Received April 17, 2013; Accepted May 11, 2013; Epub May 22, 2013; Published June 1, 2013
Abstract: The aim of this study was to compare the results of see-and-treat procedure with the classical three-step procedure in terms
of initial cytology and LEEP reports. We searched the pathology charts of patients that had LEEP were searched retrospectively and
then they were divided into 2 groups according to the presence or absence of a cervical biopsy before LEEP. There were 116 patients in
the study. Of the patients with ASCUS/LSIL cytology and a positive cervical biopsy 48.4% had CIN 2-3 at LEEP, in contrast only 19% of
the patients without a prior cervical biopsy had CIN 2-3 at LEEP (p=0.031); there was no statistically significant difference between the 2
procedures in patients with a HSIL and ASC-H smear result (p=0.726 and p=1.0 respectively). In conclusion patients with ASC-H and
HSIL cytology see-and-treat approach seems more advantageous, avoids delay in treatment, noncompliance and risk of skipping
lesions at biopsy. (IJCEM1304013).
Keywords: See-and-treat, colposcopy, CIN, overtreatment
Address correspondence to: Dr. Nilgun Guducu, Istanbul Bilim University, Department of Obstetrics and Gynecology, Kisikli cad. No:
106 Altunizade, 34696, İstanbul, Turkey. Tel: +90 0533 6404010; Fax: +90 02163250104; E-mail: nilgun.kutay@gmail.com
