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| IJCEM Copyright © 2008-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711 |
Int J Clin Exp Med 2013;6(1):74-80
Review Article
MicroRNA expression profiles in differentiated thyroid cancer, a review
Xinying Li, Asim B Abdel-Mageed, Debasis Mondal, Emad Kandil
Department of Surgery, Tulane University School of medicine, New Orleans, LA; Tulane cancer center, Tulane University School of
medicine, New Orleans, LA; Department of General Surgery, Xianya Hospital, Central South University, Changsha, China
Received September 26, 2012; accepted November 3, 2012; Epub November 18, 2012; Published January 1, 2013
Abstract: MicroRNAs (miRNAs) are a class of short endogenous non-coding RNAs regulating gene expression in many biological
processes, including proliferation, apoptosis and differentiation. The deregulation of miRNA expression is believed to be an important
regulator of tumor development and progression of thyroid cancer. In this review, we discussed important roles and expression profiles
of miRNA in differentiated thyroid cancer (DTC) as well as the promising implication in clinical practice. (IJCEM1209007).
Keywords: Differentiated thyroid cancer, microRNA, mutations, fine needle aspiration biopsy
Address all correspondence to:
Dr. Emad Kandil
Division of Endocrine and Oncological Surgery
Department of Surgery, Tulane University School of Medicine
1430 Tulane Ave. SL-22, New Orleans, LA 70112-2699.
Tel: 504-988-7520; Fax: 504-988-4762
E-mail: ekandil@tulane.edu
Review Article
MicroRNA expression profiles in differentiated thyroid cancer, a review
Xinying Li, Asim B Abdel-Mageed, Debasis Mondal, Emad Kandil
Department of Surgery, Tulane University School of medicine, New Orleans, LA; Tulane cancer center, Tulane University School of
medicine, New Orleans, LA; Department of General Surgery, Xianya Hospital, Central South University, Changsha, China
Received September 26, 2012; accepted November 3, 2012; Epub November 18, 2012; Published January 1, 2013
Abstract: MicroRNAs (miRNAs) are a class of short endogenous non-coding RNAs regulating gene expression in many biological
processes, including proliferation, apoptosis and differentiation. The deregulation of miRNA expression is believed to be an important
regulator of tumor development and progression of thyroid cancer. In this review, we discussed important roles and expression profiles
of miRNA in differentiated thyroid cancer (DTC) as well as the promising implication in clinical practice. (IJCEM1209007).
Keywords: Differentiated thyroid cancer, microRNA, mutations, fine needle aspiration biopsy
Address all correspondence to:
Dr. Emad Kandil
Division of Endocrine and Oncological Surgery
Department of Surgery, Tulane University School of Medicine
1430 Tulane Ave. SL-22, New Orleans, LA 70112-2699.
Tel: 504-988-7520; Fax: 504-988-4762
E-mail: ekandil@tulane.edu
