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| IJCEM Copyright © 2008-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711 |
Int J Clin Exp Med 2010;3(3):186-191
Original Article
Ability of the ankaferd blood stopper® to prevent parenchymal bleeding in an
experimental hepatic trauma model
Erhan Aysan, Hasan Bektas, Feyzullah Ersoz, Serkan Sari, Arslan Kaygusuz, Gulben Erdem Huq
Istanbul Educational and Research Hospital, Department of General Surgery, Emirhan Cad. No: 3 Besiktas - Istanbul, Post code:
80700, Turkey.
Received April 28, 2010, accepted June 25, 2010, available online June 30, 2010
Abstract: Hepatic parenchymal bleeding (HPB) is a major problem following both trauma and elective hepatic procedures. The present
study investigated the effect of the Ankaferd Blood Stopper® (ABS) on HPB. Method(s): A total of 20 rats were used. After creating a
laceration model in the left lateral hepatic lobe, the area was compressed for 3 minutes with the ABS in the rats in group 1 (n=10) and
with 0.9% NaCl-soaked gauze in the rats in group 2 (n=10). Results: The mean change in haematocrit levels between baseline and the
24 hour values in group 1 was lower than group 2 (p=0.045). The mean perioperative bleeding in group 1 was lower than group 2
(p=0.003). The histopathologic evaluation revealed that there were no differences between the groups with respect to areas of necrosis
(p=0.107) or inflammation (p=0.135). Conclusion: Although the ABS does not stop HPB completely, it ensures a statistically significant
reduction in HPB.(IJCEM1004003).
Key words: Bleeding, parenchyma, hepatic, trauma, elective, surgery, Ankaferd Blood Stopper
Full Text PDF
Address all correspondence to:
Erhan Aysan, MD
Emirhan Cad. No: 3 Besiktas
Istanbul, Post code: 80700, Turkey.
Tel: +90-212-2279042
Fax: +90-212-8758620
E-mail: dr@webcerrah.com
Original Article
Ability of the ankaferd blood stopper® to prevent parenchymal bleeding in an
experimental hepatic trauma model
Erhan Aysan, Hasan Bektas, Feyzullah Ersoz, Serkan Sari, Arslan Kaygusuz, Gulben Erdem Huq
Istanbul Educational and Research Hospital, Department of General Surgery, Emirhan Cad. No: 3 Besiktas - Istanbul, Post code:
80700, Turkey.
Received April 28, 2010, accepted June 25, 2010, available online June 30, 2010
Abstract: Hepatic parenchymal bleeding (HPB) is a major problem following both trauma and elective hepatic procedures. The present
study investigated the effect of the Ankaferd Blood Stopper® (ABS) on HPB. Method(s): A total of 20 rats were used. After creating a
laceration model in the left lateral hepatic lobe, the area was compressed for 3 minutes with the ABS in the rats in group 1 (n=10) and
with 0.9% NaCl-soaked gauze in the rats in group 2 (n=10). Results: The mean change in haematocrit levels between baseline and the
24 hour values in group 1 was lower than group 2 (p=0.045). The mean perioperative bleeding in group 1 was lower than group 2
(p=0.003). The histopathologic evaluation revealed that there were no differences between the groups with respect to areas of necrosis
(p=0.107) or inflammation (p=0.135). Conclusion: Although the ABS does not stop HPB completely, it ensures a statistically significant
reduction in HPB.(IJCEM1004003).
Key words: Bleeding, parenchyma, hepatic, trauma, elective, surgery, Ankaferd Blood Stopper
Full Text PDF
Address all correspondence to:
Erhan Aysan, MD
Emirhan Cad. No: 3 Besiktas
Istanbul, Post code: 80700, Turkey.
Tel: +90-212-2279042
Fax: +90-212-8758620
E-mail: dr@webcerrah.com
